Senescence of human skin-derived precursors regulated by Akt-FOXO3-p27KIP1/p15INK4b signaling
نویسندگان
چکیده
منابع مشابه
The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro
Skin-derived precursors (SKPs) are embryonic neural crest- or somite-derived multipotent progenitor cells with properties of dermal stem cells. Although a large number of studies deal with their differentiation ability and potential applications in tissue damage repair, only a few studies have concentrated on the regulation of SKP self-renewal. Here, we found that after separation from their ph...
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ژورنال
عنوان ژورنال: Cellular and Molecular Life Sciences
سال: 2015
ISSN: 1420-682X,1420-9071
DOI: 10.1007/s00018-015-1877-3